Liothyronine is the pharmaceutical name for the synthetic version of the naturally produced hormone **Triiodothyronine (T3)**. It is a thyroid gland hormone that is **four times stronger** than Levothyroxine (T4).

Primary Application:

Liothyronine is primarily used by athletes in the final **4–8 weeks** before competition to achieve the lowest possible body fat levels. Because Liothyronine increases metabolism far more intensely than the weaker Levothyroxine, an accelerated fat burn occurs due to increased metabolism of:

• Carbohydrates
• Proteins
• Fats

Due to the high potency of Liothyronine, the increased metabolism affects not only fat but also protein, leading to a **risk of muscle loss**. Cautious protocols and adequate muscle protection are essential:

• **Required Protection:** Simultaneous use of strong anabolic/androgenic steroids (e.g., **Stanozolol, Trenbolone, Testosterone Propionate**) or Growth Hormone to provide a protective effect.
• **Combinations:** Liothyronine is often stacked with thermogenics (e.g., Clenbuterol, Ephedrine) to maximize fat burning.

Use with Growth Hormone (GH):

Bodybuilders using Growth Hormone (GH) often take Liothyronine at a daily dose of **25–50 mcg** to cover the increased demand for thyroid hormones, as GH can lower the body's natural thyroid hormone levels (T3/T4).

Liothyronine is not a suitable substance for beginners. Beginners looking to support their diet with metabolism-boosting substances should rather use milder agents (e.g., Ephedrine), which have weaker side effects.

Severe Health Risks:

• **Thyroid Damage:** Long-term use and high doses carry the risk of permanent damage and inadequate functioning of the thyroid gland, which in the worst case may force lifelong use of thyroid preparations.
• **Cardiovascular Strain:** Caution must be exercised regarding the increased strain on the heart and circulatory system, especially when combined with other stimulants (Clenbuterol, Ephedrine).

Both **gradual introduction** and **gradual withdrawal** (tapering) are absolutely crucial to give the thyroid gland time to adjust to external dosing and then resume its own hormone production.

Dosing for Advanced Users:

• **Start of Cycle (Introduction):** Begin with 25 mcg in the morning, then increase the dose by an additional **25 mcg every 3–4 days**.
• **Maximum Dose:** Ambitious bodybuilders reach a maximum of **100–150 mcg per day** (used for 4–8 weeks, a maximum of once a year).
• **Women (Advanced):** Daily **25–75 mcg** for a period of 4–8 weeks.
• **Half-Life:** At 36 hours, a single morning intake is sufficient, though higher doses are recommended to be divided throughout the day for better gastrointestinal tolerance.

Withdrawal (Tapering):

The daily dose should be **reduced by 25 mcg every 3–4 days** until complete cessation, allowing the body to smoothly restore natural thyroid function.